Day 2 :
Canadian Association of Cosmetic Dermatology and Surgery
Keynote: The comparative study on safety and effectiveness of restorative treatments for facial lipoatrophy associated with HIV
Time : 09:30-10:00
Dr. Ali Khalifeh is a Board-Certified Dermatologist (YSMU), Board-Certified and Licensed Holistic Health Practitioner, specialized in Cosmetic Dermatology, Laser and Aesthetic Medicine. He is Current President and Chief Director of the Canadian Association of Cosmetic Dermatology and Surgery, and Teaching Professor of Medical Aesthetics Technology Program in CAMACS. He is serving as an Editorial Board member of Journal of Clinical Research in Dermatology, Symbiosis Publishing. He is also the president of Bioptima Medicals Inc., Pharmaceutical and Cosmeceutical Company in Canada.
Facial Lipoatrophy associated With HIV is one the worst adverse effects of HIV and antiviral treatments which not only impacts the quality of life by impairing self-esteem of the HIV infected patients but also is one the most complex challenges of the family members and the community to adjust with the patient’s social situation. rn Thymidine-based nucleoside analog cessation is the only proven treatment for HIV associated lipoatrophy, although plastic surgeons and dermatologists are constantly exploring the new horizons of cosmetic procedures to restore the lost fat and maintain the normal and natural look of the HIV-infected patients.rnAutologous Fat Transfer, biodegradable or permanent injectable fillers and facial prosthetics have been used for HIV facial lipoatrophy treatment and all have offered some acceptable safety and aesthetic results, but apparently there are not sufficient clinical studies in treatment of choice in facial lipoatrophy for HIV-infected patients.rnIn this article we discuss the comparative efficacy of different therapies, assessment of existence and severity of facial lipoatrophy, and treatment measures of various cosmetic procedures for HIV associated facial lipoatrophy. rn
British Columbia Academy of Medical Aesthetics and Skin Care
Keynote: Decorin that regulates dermal wound healing and reduces scar formation can also alleviates skin laxity leading to tissue tightening and wrinkle reduction
Time : 10:00-10:30
Dariush Honardoust has earned his Doctorate (Cranio Facial) from the Faculty of Dentistry, University of British Columbia. He has completed his Post doctorate from the Division of Plastic Surgery, University of Alberta and Master's degree in Anatomy & Cell Biology from University of Western Ontario. The highlights of his qualifications include excellent record of teaching and clinical and research productivity and manuscript publications, conducting research projects and training graduate and undergraduate students, student advising and curriculum development. He is the President of the Canadian Association of Medical Spas and Aesthetic Surgeons. He also serves as the teaching Professor at the prestigious BC Academy of Medical Aesthetics & Skin Care.
Small leucine rich proteoglycans, decorin and fibromuduline are extracellular matrix molecules that regulate collagen fibrillogenesis and inhibit transforming growth factor-β (TGF-β1) activity; thus, they may play a critical role in regulating scar formation and wound healing. Down regulation of decorin and fibromoduline after wound healing in deep injuries to the skin plays an important role in the development of fibrosis and hypertrophic scars. Decreased anti fibrotic molecules such as decorin and fibromuduline in matrix of deep dermis of the skin and the unique features of the associated fibroblasts including an increased sensitivity to TGF-β1 stimulation contribute to the development of hypertrophic scars after injuries involving the deep dermis. Studying the characteristics of superficial dermal injuries that heal with minimal scarring will help us identify therapeutic approaches for tissue engineering and wound healing. Decorin also promotes neocollagenesis leading to skin tightening and reduction of skin laxity, fine lines and wrinkles. Direct injection of decorin or incorporating it with hyaluronic acid based injectable soft tissue dermal fillers can substantially enhance skin rejuvenation and tightening by promoting collagen fibrilogenesis and deposition at the site of injection. Decorin leads to firmer skin when is injected in laxing areas where the sign of aging is apparent as fine lines and wrinkles. Further studies are warranted to explore the significant role of decorin subcutaneous treatment in increasing the quality and quantity of collagen as a skin anti-aging therapeutic strategy
University of Alberta
Time : 10:30-11:00
Barry A S Lycka is one of the most respected and accomplished Cosmetic Dermatologists in the world. Having practiced for over 25 years, he has done over 10's of thousands of liposuction, Mohs Surgery, Injections, Fat Transfer and other elaborate procedures. While practicing in Edmonton since 1989, he has written 17 books, over 30 academic papers and is host of the number one internet radio show on cosmetic surgery: Inside Cosmetic Surgery Today. He is also the Founder of Your Cosmetic Doctor: The number one internet television show on cosmetic surgery.
Breast augmentation has been the number one cosmetic procedure in the world for a number of years according to the ASPS. The modern era of silicone breasts commenced with Frank Gerow’s implantation of the patient Timmie Jean Lindsey in 1962. Despite its ubiquity and generally inert nature, silicone implants generate intense debate and litigation, particularly in America. Still, it is not without complications as they occur in 5-7% in their immediate postoperative course. The worst of these include infections and capsular contracture. What is needed is a more natural augmentation process. Fat has been used as a natural reconstructive substance. Coleman recently reported impressive results in primary BA grafting, a remarkable mean amount of 277 cc per breast. However, that poses several problems; it can become necrotic, calcify and can mimic or hide breast cancer. As a result, the authors of this paper have developed a technique of fat augmentation they have named SVELT (Small Volume Elective Lipo Transfer) that minimizes these complications. The importance of this is that it uses small volumes of fat and does the treatment serially to get the best results. To date, over 1500 cases have been studied. This is an ongoing developing project between Dr. Barry A.S. Lycka in private practice in Edmonton, Alberta, Assistant Clinical Professor at the University of Alberta and Dr. Daryl K. Hoffman, a plastic surgeon from Palo Alto, California.