Day 1 :
University of Melbourne and the Epworth Hospital
Time : 10:00-10:40
Professor Rodney Sinclair is Professor of Dermatology at the University of Melbourne and Director of SInclair Dermatology. He is Past-President of the Australasian Society for Dermatology Research, the Australasian Hair and Wool Research Society and the Skin and Cancer Foundation of Victoria.
Prof Sinclair is the co-author of the section on Dermatology in the Oxford Textbook of Medicine, the Hair Chapters in Rook and Bologna and lead author of Therapeutic Guidelines- Dermatology. He has written 13 textbooks of dermatology, and has over 400 research publications.
Sinclair Dermatology conduct clinical research in psoriasis, hair loss, urticaria, atopic dermatitis, hidradenitis suppurativa, and skin cancer prevention and treatment as well as laboratory research into stem cell biology, regenerative medicine and gene discovery.
All men and women experience some degree of hair loss with advancing age. When severe or premature it can cause significant distress.
The diagnosis of androgenetic alopecia can usually be made clinically by visual inspection of the frontal scalp and examination of follicular units with dermoscopy. In some women further investigations may be required to identify contributing factors, comorbidities such as polycystic ovary syndrome, diabetes, hypertension and hyperlipidaemia and exclude other potential differential diagnoses such as chronic telogen effluvium and frontal fibrosing alopecia.
Computer generated 3-D reconstructions of the arrector pili muscle have delivered a new model for scalp hair growth that explains how men and women with androgenetic alopecia can lose up to 50% of their scalp hair volume without visible balding; why women develop diffuse hair loss rather than complete baldness and why hair follicle miniaturization is fully reversible in alopecia areata but only partially reversible in androgenetic alopecia.
Gene associations studies have identified candidate genes and epigenetic silencing of the androgen receptor gene on the occipital scalp explain the inheritance and pattern of androgenetic alopecia.
Combination therapy of oral antiandrogen and oral minoxidil with topical stemoxydine reduce hair shedding, arrest natural progression and stimulate partial hair regrowth.
Cosmetic camouflage, scalp micropigmentation and hair transplantation complement medical therapy.
Reconstructive Surgery and Anti-aging Center, Japan
Time : 11:00 to 11:40 AM
Yohei Tanaka is one of the leading Plastic Surgeons in Japan. He directs his clinic, Society for Near-infrared Rays Research and International Photobiological Society. He conducts many researches as a Visiting Professor of Niigata University of Pharmacy and Applied Life Sciences and Lecturer of Tokyo Women’s Medical University. He has published over 20 peer-reviewed papers in English and has edited 2 international open access books regarding near-infrared. His goal is to discover the most effective near-infrared wavelengths for rejuvenation and anti-cancer therapy and to further study solar near-infrared and how best we can protect ourselves against its photoaging.
Radiation oncology is a medical specialty that involves treating various types of cancers with radiation. The radiation therapy used in treatment obtains radioactive energy from X-rays, protons or other types of energy. Near-infrared is electromagnetic radiation with wavelengths longer than those of visible light. As actively proliferating cells show increased sensitivity to near-infrared, near-infrared has been extensively investigated for its applications in cancer detection and imaging. I have elucidated that water-filtered broad-spectrum near-infrared has various biological effects including stimulation of collagen production, long-lasting vasodilation, relaxation of dystonic and hypertrophic muscles and anti-cancer effects through our histological and clinical investigation. Water-filtered broad-spectrum near-infrared can significantly suppress proliferation of various types of cancer cell lines and significantly inhibit the growth of transplanted cancer cells. In our previous studies anticancer therapy using water-filtered broad-spectrum near-infrared treatments was equally or more effective than chemotherapy and marked evidence of in vivo tumor apoptosis was observed in near-infrared-treated tumors. We have reported that water-filtered broad-spectrum near-infrared induces drastic non-thermal DNA damage of mitotic cancer cells without damaging non-mitotic normal cells. Furthermore, near-infrared can be easily administered, regulated and precisely delivered only to the targeted areas, which enables the induction of anti-cancer effects with a minimum level of discomfort and side effects. Therefore, I believe that water-filtered broad-spectrum near-infrared treatment may be beneficial for treating cancer. I would like to introduce the various biological effects of water-filtered broad-spectrum near-infrared and a potential application for treating various types of cancers.
University of Western Australia, Australia
Time : 11:40-12:20
Patrik J Tosenovsky provides services for all vascular patients, sub-specializing in chronic venous disease, diabetic foot and vascular access. He performs sub-specialty procedures including; deep vein reconstructions through keyhole surgery for patients with severe post-thrombotic syndrome, surgical management of extensive DVT, laser and sclerotherapy for varicose veins, micro-vascular procedures, including free tissue transfer for non-healing ulcers. He was trained in Europe as a Vascular and Transplant Surgeon and has practiced as a Consultant since 2000. He has completed his PhD in Diabetic Foot and his FRACS in Sydney, Australia. He has always been active in research and teaching at both undergraduate and postgraduate levels. He is currently participating in an early stage clinical study in Western Australia that will look at innovative diagnostic tools for arteriovenous fistulas for patients on haemodialysis.
The aim of this study was to analyze how safe and reliable is iliac vein stenting in patients with non-thrombotic iliac/femoral vein lesions. Prospectively maintained database of 50 consecutive patients was analyzed. Total 53 iliac veins were stented for non-thrombotic lesions (compression of iliac vein) during 2011-2016. Patients suffered from variety of symptoms including intractable swelling (C3), healed ulcers/lipodermatosclerosis (C4), active venous ulcer (C5), venous claudications or a combination of symptoms. Patients’ median age was 72 years (range 22-90); male to female ration 21:29 and median follow up was 8.2 months (range 1 to 36 months). Perioperative mortality was 0%, surgical complication rate in 30 days was 2% (1 stent thrombosed; primary stent patency rate was 96%), 2 patients developed a non-surgical complication during first 30 days. 68% of patients with active leg venous ulcer (C6) healed within 12 weeks post intervention. Non-thrombotic iliac vein lesion stenting is safe and reliable and it might be suitable for selected group of patients with advanced skin changes due to venous hypertension.
Location: Melbourne, Australia
Aneja Skin Care Centre, India
Dr. Simran Pal Singh Aneja has completed his MD Dermatology at the age of 28 years from Devaraj Urs University(Kolar, Karnataka) and MBBS from Sri Ramachandra University(Chennai). He is the director of Aneja Skin & Hair Centre, a premier Skin & Hair Centre.
Ablative Fractional Co2 Laser therapy is considered by most as gold standard for atrophic acne scars although it is associated with prolonged erythema at treated site, longer downtime which may affect the daily lives of patients. Autologous Platelet-rich plasma (PRP) is known to enhance wound healing and has been shown to act as a potential adjuvant with Fractional Co2 laser for the correction of acne scars. The objective of this study was to evaluate the synergistic effect of autologous platelet-rich plasma (PRP) combined with fractional CO2 laser therapy for acne scars. 55 patients with moderate to severe atrophic facial acne scars of different morphologies were enrolled . 48 of them completed the study. Of those who completed, each underwent 3 sessions of PRP combined with fractional co2 laser therapy at 6-8week intervals. Clinical photographs were taken and patients were assessed at each session. Final assessment was done 5 months after the last session using a four-point scale for clinical improvement of skin smoothness .More than 75% improvement was labeled as excellent response , 51-75% as good, 26-50% and 0-25% as fair and poor respectively . 12 patients (25%) showed excellent improvement 22(45.8%) and 14(29.2%) patients demonstrated good and fair response respectively. Average duration of operated site erythema and edema was 3-5 days. Two patients developed post inflammatory hyperpigmentation which lasted 6-12 weeks. PRP with ablative fractional co2 laser therapy is a good combination for treating acne scars with higher patient satisfaction for clinical improvement as well as shorter downtime .
- Dermatological Diseases and Disorders
Location: Melbourne, Australia
Queen Elizabeth Hospital, UK
Zainab Sawafta has completed her MBBS from the University of York and is currently in her second year of Medical training. She has completed her first year of training in Queen Elizabeth Hospital Birmingham, which is recognized as one of the leading hospitals in Europe. She is currently continuing her training in Birmingham. She is very enthusiastic about pursuing a career in dermatology in the near future and has carried out various projects and voluntary placements in the field.
Introduction: Basal Cell Carcinoma (BCC) is responsible for a significant healthcare burden, particularly among Caucasian populations. Its locally invasive and destructive potential results in high morbidity, if left untreated. The gold standard for this is surgical excision with histological analysis of margins. In the UK, BCC excisions are carried out in both primary and secondary care settings. Success of therapy is assessed through evaluation of excision margins, which we have compared between specialties.
Methods: A retrospective analysis of BCC histology reports was carried out over four months, analyzing excision margin based on specialty and operator experience. Biopsies were excluded. Data was taken from a District General Hospital histopathology laboratory, which analyses BCC specimens from Dermatology, Plastic Surgery, Oculoplastics, ENT and GP Departments.
Results: 549 patients had 629 lesions excised. Excisions carried out by specialty were as follows: 516 by Plastic Surgery, 78 by Dermatology, 26 by General Practice, 6 by Oculoplastics and 3 by ENT. Dermatology completely excised 86% of lesions with 8% less than 1 mm margin and 6% involving margins. Similarly, 85% of lesions were completely excised by Plastic Surgery, 10% less than 1 mm and 4% involving margins. GP completely excised 63% with 27% less than 1 mm and 8% involving margins. 18% of incomplete excisions were carried out by consultants.
Discussion: Findings show that specialties with higher caseload, therefore greater operator experience exhibit more favorable results when it comes to BCC excisions, compared to primary care. Consultants were far less likely to have incomplete excisions, compared to trainees or GPs.
Dr. Salim Mulla has completed his Ayurvedacharya – BAMS from Shivaji University , Kolhapur in 1998. He completed M.S.(Ayurvedavachaspati) in 2004 from University Of Pune. He has done studies in Medical Genetics from Maharashtra University of Health Sciences in 2008. Also done studies in Preventive Ayurvedic Cardiology & Panchakarma from Mahatma Gandhi University Meghalaya & Madhavbaug Institute Thane in 2013. Running Speciality Ayurveda Hospital at Islampur - Sangli Maharashtra. He has published 3 papers in reputed journals. He is engaged in research work in obstetrics & gynaecology, infertility, vitiligo & Ayurveda. He has presented scientific Papers at various National & International seminars & conferences.
This is a single blind randomized clinical study on patients of vitiligo , a disease rather difficult for cure. Aetiology is multifactorial, it may be hereditary , autoimmunue, hormonal imbalance , dietary, stress , secondary to other systemic diseases like diabetes mellitus, hypothyroidism etc. This study is carried out on 200 outdoor patients suffering with vitiligo. Patients from both sexes, from age group five to seventy years complaining mainly as white patches are studied. Patients are treated with ayurvedic polyherbal powder mixture containing Psoralia corylifolia ( Bakuchi) as main ingredient supplemented with local application and phototherapy (natural). Most of the patients undergo intermittent bodypurification i.e. shodhana – panchakarma treatments like vamana ( therapetic emesis ) , Virechan ( purgation), Basti ( enematous treatment for Vaatadoosha) , raktamokshana etc as per ayurvedic guidelines. Duration of treatment is of one month to one year depending upon response & requirement for the treatment. Followup is biweekly to monthly. The response to treatment is observed in terms of reduction in area of depigmentation after treatment. Complete cure is noted in 12 % patients. Good result is noted in 18 % cases , moderate in 45 % cases and mild result in 25% cases noted. The result is statistically highly significant at 0.1% level. No major side effects of the treatment given observed. The treatment is effective in all types of vitiligo. The results of internal medications & local treatment are aggrevated specially after panchakarma treatment.
Southern Philippines Medical Center, Philippines
Time : 14:45-15:15
Friend Philemon M Liwanag has completed his Doctor of Medicine degree at the Manila Central University-FDT Medical Foundation. He is a currently a second year Dermatology Resident at the Southern Philippines Medical Center in Davao City, Philippines.
Histoid leprosy is recognized as a rare form of leprosy with a heavy bacillary index. De novo is a peculiar type of histoid leprosy characterized as an initial clinical presentation without previous treatment with multidrug therapy. Further, published reports have shown the possible participation of skin other than respiratory droplets in leprosy transmission. We report a case of de novo histoid leprosy in a 30 year old man, who initially presented with a hyperpigmented papule which progressed into a shiny nodule over a tattoo site on his left upper arm. The lesions became generalized with symmetrical distribution. Histopathological studies revealed findings consistent with the diagnosis. Histoid leprosy was first described in the Philippines, which exemplifies the challenge to leprosy eradication. Thus, this finding that tattooing as likely cause of inoculation of histoid leprosy in this post-elimination era generates important consideration.