Murada Abobaker Muttardi
University of Benghazi, Libya
Title: A comparative study of clinical response to topical minoxidil and topical corticosteroids in adult Libyan patients with alopecia areata in Jumhouria Hospital in Benghazi
Biography
Biography: Murada Abobaker Muttardi
Abstract
In clinical study of alopecia areata in patient including 50 cases presented to Jumhurya Hospital Benghazi – Libya in period from January 2012 to May 2012, showed a preponderance in female (M:F 1:1.3) and the majority of patients (74%) were below 40 years of age. Family history of alopecia areata was present in 18%. The common patterns of alopecia areata observed in our study were: Patchy seen in 86%, majority (80%) of patients presented with (1-3) patches, atopy was recorded in (82%) of cases, associated disease in (4%). Nail changes were noted in 42% of cases topical monetasonefuroate 0.1% showed significant better response compared to minoxidil 0.2% in the treatment of patchy AA. Side effects itchy, redness and headache were observed in three patients, who treated with minoxidil 0.2% and there is no side effects observed in patients who treated with topical monetasonefuroate 0.1%. Minoxidil has a significant stimulatory effect on hair growth in AA and it can be used as an adjuvant in the treatment of AA with topical monetasonefuroate 0.1%. The combination treatment may yield a better clinical response than either of the agents used singly as the mechanism of action of both agents are totally different.