Hyeon Jeong Park
Sungkyunkwan University School of Medicine, Korea
Title: Superficial CD34+ Fibroblastic Tumor on the Plantar Foot
Biography
Biography: Hyeon Jeong Park
Abstract
Fibroblastic mesenchymal tumors show a spectrum of biological behavior, from benign to malignant. We here in report our experience of a distinctive features of superficial CD34-positive fibroblastic tumor (SCPFT), which is a newly described neoplasm, previously undescribed low-grade fibroblastic tumor of the superficial soft tissues.
A 45-year-old man presented with subcutaneous nodular lesion on the mid foot area of the right sole. The lesion was near the area of skin graft of the foot, which undergone traumatic amputation by traffic accident 40 years ago. The right foot MR examination revealed 2.0 x 1.6 x 0.8 cm sized enhancing mass involving skin and subcutaneous layer. After total excision with supralesional flap surgery, the histopathological study of the 1.9 x 1.8 x 0.5 cm sized mass revealed some nodular growing pattern of atypical spindle cell proliferative lesion with distinctive angiomatosis, moderate nuclear atypia, admixed some inflammatory cells in fibro-fatty tissue, and mitotic figures of 1/10 HPFs. The CD34 stain showed diffusely positive reaction for the lesion, and the expression of Ki-67 protein was very low. Finally, the patient was diagnosed with SCPFT.
To date, 42 cases of SCPFT have been reported. The actual incidence rate of this entity is likely much higher due to the lack of sufficient recognition of this tumor. Herein, we report a rare case of the SCPFT to enhance the recognition and diagnostic level of the disease.