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Ajit K Verma


Ajit K Verma

University of Wisconsin, USA

Biography

Ajit K Verma has obtained his PhD in 1972 at the Flinders University of South Australia, Adelaide, Australia and Postdoctoral training in 1976 at the McArdle Laboratory, University of Wisconsin, USA. Currently, he is a full Professor in the Department of Human Oncology, University of Wisconsin, USA. His major findings include generation of PKCε transgenic and conditional PKCε knockout mice, identification of PKCε downstream molecular targets (Hsp90, Stat3, cytokines) and their role in ultraviolet radiation carcinogenesis. He was the first to report that Hsp90 inhibitor 17AAG can be topically applied to prevent development of SCC.

Abstract

Abstract : Topically applied Hsp90 inhibitor 17AAG inhibits ultraviolet radiation induced cutaneous wrinkles and squamous cell carcinomas