Clinical and Experimental Dermatology

Biography

Biography: Svyatenko Tetyana

Abstract

The skin is affected in 20-25% of all cases and is very important in the diagnosis, prognosis and course of sarcoidosis. In recent years the number of cases of sarcoidosis increased in Ukraine. We are observed men, born in 1967, complained about skin rash in the area of the upper third of the back slightly itching. The process progresses slowly(2 years). He was treated with the diagnosis: multiple warts? Lichen planus? – without effects. Patient also has a history of atopic dermatitis, androgenetic hair loss. The parents and close relatives are healthy. Physical condition was satisfactory. Pathological skin process is localized on the upper back. Rush is represented by single knots, up to 2 - 5 mm in diameter, multiple scattered and confluent lesions up to 3 cm in diameter, the colour red and pink, with telangiectasias, soft-elastic consistency, the surface smooth and shiny. On diascopy symptom of "dust", the phenomenon of "cape". Blood test results: normal range. Punch biopsy was provided. Histological investigation shown epidermis without changes, multiple epithelioid - cell granulomas are determined in papillary and reticular dermis with the presence of single giant polynuclear cells. Granulomas have clear boundaries, with the presence of single lymphocytes around some of them. When painting on Alcian blue PAS + cells of fungi have been identified. The basement membrane is within norm. No dermal mucin. The diagnosis: Cutaneous sarcoidosis. In our opinion, the case described introduce certain interest in the daily practice of a physician - clinician.This condition is rare and difficult to diagnose.