Anzhela Grevtseva
Russian Medical Academy of Postgraduate Education
Russia
Title: Important aspects of Demodex diagnostics
Biography
Biography: Anzhela Grevtseva
Abstract
Background: Demodex-mites live in sebaceous or meibomian glands and hair follicles. Demodex is possible to detect by scraping, at extraction of ducts contents of sebaceous glands or remove the eyelashes and/or eyebrows; standardized skin surface biopsy (SSSB); skin biopsy with the subsequent histology of the received samples; dermatoscopy; skin biopsy with histological analysis. In medicine there will always be a demand for informative, high-tech and non-invasive diagnostic methods. These methods include confocal laser scanning in vivo microscopy (CLSM).
Aim: To compare the efficiency of diagnostics of demodecosis for patients with acne and rosacea by various methods.
Materials & Methods: We observed 60 patients with acne and rosacea complicated demodecosis (group I), 60 patients with acne and rosacea without demodecosis (group II) and 30 healthy volunteers (group III).
Results: On the CLSM the mite was found in all patients with demodecosis. Demodex was defined as rounded or long cone-shaped formations in the hair follicle orifices and sebaceous glands. During the inspection of patients from group II, it was succeeded to identify mites at 10 (13%) patients at whom the method of scraping was shown by negative result. At study of healthy volunteers from group III, the method of the CLSM found Demodex mites in follicles in 6 people (8%).
Conclusion: As a result of the research of patients with acne, rosacea and healthy volunteers, there was an established high informational content of the CLSM in diagnostics of a demodecosis and its advantage over usual light microscopy.