Golnoush Kouhihabibidehkordi
Shahrekord University of Medical Sciences, Iran
Title: Skin wound and white tea
Biography
Biography: Golnoush Kouhihabibidehkordi
Abstract
Introduction: Skin wound is a cut or tear happen to skin which protects our body from foreign factors and dehydration. By considering the positive effect of green tea on the surgical and burn wounds and similarities between green tea and white tea and the more antioxidant properties of white tea in comparison with green tea, this study is designed to evaluate the effect of white tea extract on healing process of excisional skin wounds in rats.
Methodology & Theoretical Orientation: For this experiment, 105 healthy male Wistar rats (200-250 g) were randomly divided into two types: Ointment (Eucerin) and gel. Each type was divided into three groups containing 21 rats: Control group ( which is the same in both types), vehicle (Eucerin)-treated group, white tea 5% ointment (Eucerin) treated group, vehicle (gel)-treated group, white tea 5% gel treated group. On the day 0, excisional skin wounds were created. Treatment was begun at the day one and repeated every day at the same time until day 15. Pathologic samples were taken at days four, seven and 15 for histopathological examinations. At the end, by the use of SPSS software and Kruskal-Wallis analysis of variance, collected data was analyzed and P value <0.05 was considered as significant.
Findings: Results of this study shows that in day seven, reepithelialization and granulation tissue of control group is significantly (p<0.05) more than white tea treated group and the inflammation of white tea treated group is significantly (p<0.05) more than control group.
Conclusion: In this study, 5% white tea extract could not help the healing process of the skin wounds in rats.