Yuzhi Jiang
Shanghai Jiao Tong University
China
Title: Exploring the three dimensional structure of dermal tissues
Biography
Biography: Yuzhi Jiang
Abstract
The dermal tissues are composed of collage fibers and have been researched many years. The composite and three dimensional structure of collagen protein, collagen fibrils, collagen fiber has been clarified, however, the three dimensional structure of the extracellular matrix of dermal tissues has not been known, which impede the development of skin tissue engineering and skin regeneration. For example, the current skin tissue engineering products use the non-woven structure as the scaffold, which confirmed unsatisfactory after clinic usage. The other question is how the collagen fibers wove into the normal ECM during ontogeny and after wound healing is still unknown. This research will focus on the exact three dimensional mesoscopic structures of dermal tissues and would like to uncover the mechanism of the knit of collagen fibers, provide the golden standard to evaluate the skin tissue engineering product and regulate the wound healing.