Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 16th European Dermatology Congress Milan, Italy.

Day 1 :

Keynote Forum

Mel Ziman

Professor Edith Cowan University Australia

Keynote: Blood based biomarkers for diagnosis, prognosis and monitoring of patients with melanoma.

Time : 09:40 to 10:10

OMICS International Euro Dermatology 2017 International Conference Keynote Speaker Mel Ziman photo
Biography:

Prof Ziman is Associate Dean of Research and Chair of the HREC at Edith Cowan University. Her research focuses on blood based biomarkers for melanoma. Her team have been awarded > $7 million in funding from the National Health and Medical Research Foundation as well as international funding agencies and pharmaceutical companies and collaborates closely with world leading clinicians and researchers. In 2016 she received the Vice Chancellor’s Award for Research. Prof Ziman has been a member of the Parliamentary Committee on skin cancer, and is a member of grant review panels for national federal agencies, Cancer Councils and international review panels. She has published over 100 papers and has over 2000 citations

Abstract:

 

Current methods of melanoma diagnosis and prognosis are at times problematic and limited to observation of tumour tissue by histology or imaging. The analysis of blood based, tumour specific products including autoantibodies, circulating tumour DNA (ctDNA) and circulating tumour cells (CTCs), now provides early rapid, accurate and quantitative measurements of tumour presence and /or burden. In our studies, we utilised protein arrays, mutation-specific droplet digital PCR and microfluidic devices to measure autoantibodies, mutant tumour DNA (ctDNA) and circulating tumour cells (CTCs), respectively, in patients with very early to advanced stage metastatic melanoma. Autoantibodies were detected in very early stage patients (n=150) at significantly higher concentrations than those in healthy controls (n=150). A diagnostic combination of 10 autoantibodies has been identified that can be utilised as an accompaniment to current clinical measures. 

For metastatic melanoma we utilised ctDNA and CTCs to detect and monitor tumour burden during treatment of patients with targeted therapies (n=47) and/or immunotherapies (n=48). CTCs and/or ctDNA were detected in 70% to 80% of samples prior to treatment. Levels of ctDNA and CTCs decreased in response to therapies, prior to, or concurrently with radiographic response. Moreover, patients with no, or low, levels of ctDNA and CTCs at baseline had significantly longer PFS. In addition, CTC subtypes, including those positive for PDL1, predicted response. In conclusion, our studies demonstrate the utility of blood based liquid biopsies to assist with diagnosis, prognosis and monitoring of melanoma patients.

 

Keynote Forum

Thomas Haffner

Vascular and cosmetic surgeon, Germany

Keynote: Centro facial rejuvenation: Facial plastic surgery or volume lifting

Time : 10:55 AM to 11:25 AM

OMICS International Euro Dermatology 2017 International Conference Keynote Speaker Thomas Haffner  photo
Biography:

Thomas Haffner is a Board Certified Reconstructive, Vascular and Cosmetic Surgeon in Germany. He was trained in the Reconstructive-Plastic Surgery and Senology Section at the Semmelweis University, Budapest. He is specialized in Vascular Surgery and has worked as Department Leader in German clinics. He was a Resident Assistant under Professor Rettinger in Ulm. In 2000, he established his private clinic for vascular-reconstructive and aesthetic surgery in Cologne, Germany. His primary focus is the breast and facial surgery using minimal invasive and endoscopic methods. He invented the innovative vertical scar free reconstructive 3D mastopexy. 

Abstract:

Background: For correction of the lateral facial portions, jaws and neck the "old" cervicofacial facelift is very suitable. But our attractiveness depends also on the central facial triangle, which is based on cheek bones, orbita and eyes, nose, lips and chin. The midface is an important part of this central facial triangle. Depletion and ptosis are early signs of aging with weakening of the soft tissue´s strength.

Aim: To compare to conservative and endoscopic operative ways of centro-facial rejuvenation and to evaluate a combined method of centro-facial rejuvenation without any facial scar. The new methods consist of a new endoscopic, scar free facelift and from an additive midface volume reconstruction.

Methods: By the first signs of centro-facial depletion, the author uses volume augmentation by long-lasting hyaluronic acid, Ca-hydroxyapatit or fat. To compensate sagging tissues a combination of suspensions-loops with thread lifts are very popular. Temporal endoscopic or sub-orbicular midface lift works very effective against centro-facial aging.

Findings: Most of the centro facial, sub-orbicular and cheek augmentations was made using long term hyaluronic acid volume augmentation. It is a quick and practical outpatient treatment, which is suitable for large quantities of patients. Radiesse and Radiesse liquid lifting works even longer. Radiesse has the ability even of nose correction because of its high viscosity. PRP-mixed hyaluronic acid or Radiesse seems working very good as well, however should be repeated in a shorter following period. Volume restoration with fat grafting, micro-fat, nano-fat has the advantages and privilege for full face application and sculpture, for that large volume of fat between 50-80 ml per face was applied.

Results: Depletions can be well managed by volume augmentation. But authors found much better results with facial plastic surgery plus volume restoration as volume restoration only. Scar-less facial plastic surgery such as the author´s Temporal Endoscopic Facelift opens new perspectives and indications for reconstruction of the aging face and works especially in the central facial portion.

 

 

Keynote Forum

Leonardo Corcos

Founding Member and Vice president of the Italian Society of Phlebolymphology. University of Siena Sassari and Udine (1990-2010)

Keynote: Recurrent Skin Telangiectasia

Time : 10:10 AM to 10:50 AM

OMICS International Euro Dermatology 2017 International Conference Keynote Speaker Leonardo Corcos photo
Biography:

Leonardo Corcos has a Degree in Medicine in 1970. Specialyzed in General, Emergency and Vascular Surgery from 1976 to 1993. Founding Member and Vice president of the Italian Society of Phlebolymphology. Professor in the University of Siena, Sassari and Udine Italy (1990-2010).”Member of the Italian Society of Phlebolymphology from 1986. Scientific research in Phlebology from 1977 with 385 scientific publications mainly on Phlebology, Vascular Surgery and Diagnostics, of which 184 published in scientific journals, text books and congress proceedings, and 201 abstracts

Abstract:

Primary and secondary skin telangectasia (ST) are mainly a cosmetic problem, they can be extended to the whole body but he majority of them develop in the lower limbs. They are one of the most difficult challenges in vascular and cosmetic Medecine owing to a high number of early and late recurrences post-treatment and progressive trend. The aim of the study was to identify and treat the main anatomical and functional causes. Patients were systematically subjected to duplex venous ultrasound examination. Chronic venous insufficiency and reticular varicose veins were investigated. In 467/529 cases (88.2%) recurrent telangiectasia of various anatomical types were found. The main causes as chronic venous insufficiency and/or reticular varicose veins were preventively treated. The majority of ST were treated by liquid sclerotherapy and a small number of red ST were treated by 808 nm diode surface or endovascular laser. The treatment was guided both by transillumination and polarized light. Immediate elastic compression with refrigerant padding was applied. Only 271 (51.29%) patients were controlled from 1 to 10 years (mean follow-up 6 years, 8 months) and retrospectively studied from 2002 up to 2012. ST were combined with truncular varicose veins in 22 cases (4.1%). Persistence of reticular varicose veins in the 92.2% of the cases, atypical perforators in the 13.6%, were the main anatomical causes of recurrence. Inadequate or uncomplete treatment limited to peripheral ST was observed in the majority. Stable results in 23/271 cases (8.4%), a progressive trend and essential recurreces in 45/271 (16.9%), worsening in 4/271 cases (1.4%) were observed. Improvement of the clinical and cosmetic outcome can be obtained by etiological treatment with the use of new tecnology of light sources and refrigerant elastic compression.

 

  • Traditional Chinese Dermatology
Location: 16
Speaker

Chair

Elvan Sarac

Florida College of Integrative Medicine. USA

Session Introduction

Elvan Sarac

Florida College of Integrative Medicine, USA

Title: Facial cosmetic acupuncture: New interpretation of ancient secrets and effective protocols in different cases/review

Time : 11:30 to 11:55

Speaker
Biography:

Elvan Sarac ìs working as Assistant Profesor of Family Medicine at Yeditepe University Faculty of Medicine, Istanbul. She has a Master Degree on Traditional Chinese Medicine from Florida College of Integrative Medicine

Abstract:

Facial cosmetic acupuncture (FCA) is the use of acupuncture on the face, head, and neck for cosmetic purposes. It can be traced back as far as 2000 years ago, as documented in the Yellow Emperor’s Inner Classic.  Several different types of FCA are practiced. Each one is based on a channel system specifically to promote the free flow of qi and blood. It is used to regulate Yin and Yang, and to regulate excess and deficiency. These unbalanced conditions can cause facial aging, bags under the eyes, wrinkles and dark circles around the eyes, and can be improved with the correct application of acupuncture techniques. The treatments can be adjusted depending on the type of needle techniques used and point prescription chosen. Besides needling, cupping, auricular points, moxa and herbal prescriptions can also enhance the results. Utilizing the correct special channels and points for each different indication is the key of facial enhancement. For example; specific points of Ren, bladder and/or kidney channels could be the best option for facial swelling and puffiness. Gallbladder channels and points are best for wrinkles around eyes and Crow's feet.  Recent studies showed promising results as a therapy for improving facial elasticity, aging of the neck. FCA can also be helpful adjunct; to go alone with more conventional forms of facial cosmetic procedures like plastic surgery, fillings and mesotheraphy injections. Protocols vary according to patient conditions. However 10 combined treatments are typically adapted.  FCA, as a part of Integrative Medicine, focuses on the integration of traditional methods with conventional. It encompasses a broader understanding of nature of facial aging, and addresses the physical as well as emotional and spiritual needs. In spite of widespread use of FCA, scientific evidence of its effectiveness is still limited hence, better designed research is needed. 

Jeanie Leddon

University of Colorado, USA

Title: Non-invasive body shaping treatments

Time : 11:55 to 12:20

Speaker
Biography:

Jeanie Leddon obtained her PhD in Chemistry from the University of North Carolina, Chapel Hill and MD from Cornell Weill Medical College in New York. She has done her internship from Yale-New Haven and Dermatology Residency from the New York University. She co-founded Boulder Valley Center for Dermatology in Colorado and serves as a Clinical Associate Professor at the Cosmetic Dermatology Clinic of Colorado University Medical School, USA.

Abstract:

Excess deposit of local fat can be stubborn and difficult to eliminate with diet and exercise alone. Liposuction had been the mainstay for removal of localized excess adipose tissue. Non-invasive methods to permanently reduce excess localized body fat can offer safer, less painful, reduced healing time and cost in body shaping. Cryolipolysis selectively freezes fat cells and allows the body’s natural mechanism to permanently remove the frozen fat cells without damage to the overlying skin. Deoxycholic acid in the body aids in breaking down and absorbing dietary fat. This chemical can be synthetically manufactured and injected into submental fat to permanently destroy localized fat. Other devices utilize ultrasound, radiofrequency or laser energy to destroy fat cells. Given the myriad of growing number of treatment options for non-invasive body shaping, learning about the pros and cons of some of these treatments is important to provide the best care for the growing number of people seeking aesthetic body contouring.

Abnoeal Bakus

Physicians Laser and Dermatology Institute, LLC Chicago, IL United States of America

Title: New technique for the treatment of active acne after failure of Accutane, antibiotics and topical Rx’s, also a non-prescription approach to treatment

Time : 12:20 to 12:12:45

Speaker
Biography:

Dr. Bakus received his Ph.D. in Bio-Laser Research through the Department of Physics at the Illinois Institute of Technology, after receiving a Masters in Radiobiology at DePaul University. He did post-graduate work in laser-tissue interaction at Northwestern University Department of Dermatology and then a researcher in the Department of Biomedical Engineering. For more than 20 years, has been involved in laser skin studies. Dr. Bakus has been Co-Director of Clinical Research at Physicians Laser and Dermatology Institute, participating in and overseeing all ongoing projects. He is an author of multiple medical articles and chapters, and has been involved in developing patents and teaching laser therapy at various medical seminars around the world. 

Abstract:

Adult acne can be challenging to treat. Laser therapy has made advances in treating inflammatory acne. Some of the successful laser devices used may also reduce hair growth which would be undesirable in the beard region of male patients.

Aim: To evaluate a device based, non-topical acne medication or oral antibiotic treatment of active acne over the beard area.

Study: A total of 10 male patients with moderate to severe acne over the beard region were treated. Patients stopped using all the topical and oral anti-acne medications. Skin types included I-IV. A QSYAG laser at 1064 nm, 6 mm and 0.9-1.3 j/cm2 was used for therapy. Patients were treated every 2 to 4 weeks depending on their level of acne severity.

Results: Patients responded with a significant reduction in acne lesions. At least 6 sessions were administered. There were no adverse effects except for immediate transient erythema and edema. Long term results were maintained after therapy. Beard hair growth remained at pre-laser therapy levels.

Conclusion: Laser therapy is an effective and safe method for treating the male beard area in patients with inflammatory acne. Appropriate laser selection and parameters are necessary to achieve.

Eleonora Dubljanin

Institute of Microbiology and Immunology, University of Belgrade, Belgrade, Serbia

Title: Epidemiologic characteristics and risk factor identification in patients with suspected onychomycosis

Time : 12:45 to 13:10

Speaker
Biography:

Eleonora Dubljanin is working as an Teaching Assistant at the Institute of Microbiology and Immunology, Faculty of Medicine at the University of Belgrade, Serbia. She completed her Magister degree in the field of Clinical and Experimental Bacteriology and got her Doctoral degree in Epidemiology from the Faculty of Medicine University of Belgrade, Serbia. She is mainly involved in research and teaching in medical microbiology, particularly in the field of fungal and parasitic human infections. She has published more than 10 papers in international scientific journals. Her research interests are medical microbiology, dermatology, laboratory diagnosis and onychomycosis.

Abstract:

Onychomycosis is a fungal infection of the fingernails and/or toenails, caused by dermatophytes, yeast and non-dermatophyte moulds. The epidemiology of onychomycosis in Serbia is yet to be fully established.

Objectives: This epidemiological study was aimed at evaluating the epidemiology of onychomycosis in a sample of the Serbian patients at risk of onychomycosis, to determine the fungal aetiological agents and to identify the possible risk factors.

Patients & Methods: The study population included 374 patients from six centers in Serbia with suspected onychomycosis. Demographic data, data about comorbidities, lifestyle, clinical aspects of onychomycosis, trauma, excessive perspiration, and personal and family history of previous onychomycosis were studied. Laboratory confirmation of diagnosis was done by direct microscopy, fungal culture and PCR.

Results: Diagnosis of onychomycosis was confirmed in 50.8% of patients, who tested positive to at least one laboratory test (direct microscopy, fungal culture or PCR). T. rubrum was predominant both on toenails (85.98%) and on fingernails (38.46%). Independent risk factors for onychomycosis were: old age (OR=2.285; p<0.001), family history of previous onychomycosis and/or tinea pedis (OR=2.452; p=0.005), excessive perspiration (OR=2.165; p=0.002), and higher degree of hyperkeratosis (OR=1.755; p=0.020).

Conclusions: Identification of the most common causative agents of onychomycosis revealed the predominance of dermatophytes and may be useful in discerning the epidemiological situation and planning preventive strategies. A significant contribution is insight in the importance of certain conventional and methods of molecular biology in the diagnosis of onychomycosis since that for the first time in Serbia molecular diagnosis was used in laboratory confirmation. These results could help in defining the optimal laboratory protocols for reliably identification of onychomycosis suitable to our local epidemiology and the economic situation. 

Fabio Ferreira Perazzo

Federal University of São Paulo, Brazil

Title: Evidenced based materials from Brazilian biodiversity used in cosmetics

Time : 13:10 to 13:35

Speaker
Biography:

Fabio Ferreira Perazzo has his expertise in the development of new products and raw materials, improving the health and wellbeing of people. He has studied with the Wajapi indigenous tribe and has lived several years in the Rainforest. His research on development of natural products has produced standardized extracts and oils for use in cosmetics and foods. Currently, he is a Professor at the Federal University of São Paulo, Faculty of Pharmacy, with over than 60 scientific publications and book chapters, supervising graduate students and working with products from Brazilian biodiversity to improve quality of life using natural products on dermatology, cancer and general inflammation problems

Abstract:

The Brazilian biodiversity has been widely study in search of new compounds, extracts, oils, fruits with high antioxidant capacity, tissue regeneration, personal care and well-being, and most of all, to improve quality of life based on natural aspects. Brazilian population is becoming aware of the value of the biodiversity. Brazilians are patriotic about resources and how to take care of the Amazon forest, sustainable and productive. Natural ingredients grown abundantly in the region, with beneficial qualities, proved to be excellent bases for cosmetics such as avocado, cocoa, coconut, babassu, mango and Brazil nut oils. The communities from the rainforest search ingredients including açai, andiroba, murumuru, Brazilian nut, buriti, copaíba, passion fruit, cupuaçu, pracaxi and patauá oil and Amazonian white clay. Açai is known for its antioxidant and anti-aging properties and is a source of phytosterols, vitamin C, polyphenols and essential fatty acids. The andiroba tree is used as an odourless insect repellant and anti-inflammatory, while annato oil has a soothing topical effect, making it useful in after-sun products. It is also rich in carotenoids, and can be used as a natural coloring agent in creams and sun tanning products. The Brazil nut is rich in selenium, vitamins and oleic acid. Buriti fruits are rich in fatty acids, carotenoids and vitamin A, increasing the skin elasticity. Copaíba is an oil tree resin that can be used for acne treatments, dandruff control, and anti-inflammatory creams, or as a woody fragrance. Cupuaçu butter is an emollient that contains phytosterols and has an unusually high level of water absorption providing a prolonged moisturizing effect. Murumuru butter is rich in oleic acid and acts as a nutritive emollient and increases the creaminess of a product. The results may contribute to the manufacture of products such as soaps, repellents, shampoos, creams and lotions.

Speaker
Biography:

Lazaros I Sakkas is working as a Professor of Medicine and Rheumatology, Chairman, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, School of Health Sciences, University of Thessaly. He is also an Adjunct Assistant Professor, Temple University School of Medicine, Philadelphia, PA, USA (Jun 2003-present) and an Adjunct Professor, Center for Molecular Medicine, Old Dominion University, Norfolk, VA, USA (March-2010-March 2017). He is the President at the Institute for Rheumatic Diseases (2011-present).

Abstract:

Recently we reported functional impairment and numerical decrease of transitional and memory IL-10-producing regulatory B cells (Bregs) in patients with psoriasis (Ps) and psoriatic arthritis (PsA). In this study we explore the relationship of IL-10+Breg cells with NK subsets expressing the IFN-γ and IL-17 pro-inflammatory cytokines.

Methods: Peripheral blood mononuclear cells from 40 PsA, 40 Ps patients and 20 healthy controls (HCs) were studied. Flow cytometric analysis was carried out with MoAbs against cell surface markers CD56, CD16, CD3, CD7, CD19, CD24, CD27 and CD38. Intracellular expression of cytoplasmic IFN-γ, IL-17 and IL-10 following bacterial CpG (ODN2006) and PMA/ionomycin stimulation was also examined by flow cytometry.

Results: The percentages of CD3-CD56+ (NK) inversely correlated with CD19+CD24hiCD38hi (transitional) Bregs and CD19+CD24hiCD27+ (memory Bregs) (p<0.05, for both). IFN-γ+ NK cells negatively associated with IL-10+Bregs. Also, IL-17+NK cells inversely correlated with IL-10+Bregs (p<0.05). IFN-γ or IL-17 production from NK cells was significantly higher in PsA and Ps compared to HCs (p<0.05 for both).

Conclusion: Deficient IL-10-producing Breg cells are associated with an increase of IFN-γ- and IL-17-producing NK cells in Ps and PsA suggesting an important pathogenetic role of pro-inflammatory innate immune cells in these diseases.

 

Grebchenko K

Bogomolets National Medical University, Ukraine

Title: Multidisciplinary approach to the treatment of aesthetic defects caused by scars

Time : 15:00 to 15:25

Speaker
Biography:

KATERYNA GREBCHENKO did her education at Ukrainian  National Medical University(2003) and then she did her internship in General surgery, dermatology. She is a M.D with speciality in Aesthetic dermatology.

Abstract:

Causing pronounced cosmetic defect scars often result in psycho-emotional discomfort and affect psycho-social adaptation. Involvement of spread areas may lead to serious functional problems. Result-disfigurement affects quality of life which, in turn, can lead to lowered self-esteem, social isolation. Thus, improvement of quality of life of patients with cicatricial origin cosmetic defects remains actual problem.

Objective: To optimize the multidisciplinary approach to the correction of the cosmetic defects caused by scars.

Materials & Methods: On the results of 228 patients’ investigation classification of cosmetic defects caused by scars was proposed. Multidisciplinary approach to their correction based on this classification was checked in 128 patients.

Results: Eight types of cosmetic defects of cicatricial origin were recognized. Selection of the treatment method depended on the pathological manifestations that have caused the greatest dissatisfaction with the patient.

Conclusion: Proposed approach to multidisciplinary correction of scars permitted to improve quality of life in all group.

Learning Objective: The learning objectives are: to evaluate what cosmetic problems produced by process of scaring cause body dissatisfaction and low patients’ self-esteem and classify them; to work up an algorithm of approach to scar correction considering the various types of cosmetic defects they cause; to optimize the multidisciplinary approach to the correction of the cosmetic defects caused by scars; and to evaluate the influence of scars treatment on the patients’ quality of life.

Amani Saad

University of London, UK

Title: News in periorbital hyperpigmentation treatment

Time : 15:25 to 15:50

Speaker
Biography:

Amani Saad is an MSc student in Aesthetic Medicine at Qween Mary University of London. She is also member of American Academy of Aesthetic Medicine.

Abstract:

Periorbital hyperpigmentation (POH), also known as dark circles, is a common complaint amongst men and women, young and elderly worldwide. However, only a few reports refer to this condition in a comprehensive and sufficient way. It is quite devastating to know that only 65 cited articles to date are indexed on PubMed journals compared to 150,000,000 results on Google search engine. POH is caused by various endogenous and exogenous factors. The etiology of POH is multifactorial with genetic or hereditary factors, post-inflammatory pigmentation secondary to atopic or contact dermatitis, excessive pigmentation, excessive periorbital vascularity and edema being common causative factors. Classification is very important in order to treat POH. It is important to make good diagnosis and to classify the nature of POH because different types of POH respond to different types of treatment modalities. Though, a combination of approaches is still the best to do in some complicated cases. Although more scientific research is needed, many treatment options are available and are considered to be relatively efficacious. Local de-pigmenting agents like Kojic acid, azeliac acid hydroquinone, non HQ bleaching agents and retinoic acid preparations are used with minimal effects. Periorbital skin resurfacing techniques are used successfully to rejuvenate the extremely delicate skin in this area. Chemical peelings, lasers, radiofrequency, hyaluronic acid filler injections, autologous fat transplantation and surgery are other treatment options used in the treatment of POH. In this research, we'll focus on the causes of periocular hyperpigmentation and the newest and most effective treatment methods available according to recent studies.

Speaker
Biography:

Professor, Tae-Aug Kim has completed his PhD at State University of New York at Buffalo, Buffalo, NY, USA, (1993). He moved to Cutaneous Biological Research Center at Massachusetts General Hospital (MGH)/ Beth Israel Deaconess Medical Center (BIDMC)/Harvard Medical School (HMS), Boston. MA. USA, focusing on the molecular mechanism of TGF signalling on skin development for his postdoctoral training (1993-1999). Then, he was appointed as Instructor at HMS/BIDMC, continuing his research on neuronal degeneration (1999-2002). After he relocated to National Cancer Institute, Bethesda, MD, USA as a senior research fellow (2002-2011), he has working on the role of epigenentic modification and heterochromatin structure on human cancer and DNA repair. He is currently Director of Skin Biology Research Center , School of Medicine, CHA University, South Korea and is working on epigenetic regulation of skin aging and cancer using 3D skin equivalent model.

Abstract:

Cacao beans contain various bioactive phytochemicals that can attenuate or delay the onset of disease condition. However, the effect of cacao powder (CP) on UVB-induced wrinkle formation and the molecular mechanisms responsible has not previously been explored. Here, we report that oral administration of CP attenuates UVB-induced skin wrinkling by regulating genes involved in dermal matrix production and maintenance. Transcriptome analysis revealed that 853 genes are down- or up-regulated with CP supplementation, compared with UVB-irradiated mouse skin controls. CP elicited anti-wrinkle effects via inhibition of UVB-induced MMP-1 expression in a human skin equivalent model and human dermal fibroblasts (HDFs). Inhibition of UVB-induced AP-1 via CP supplementation is likely to affect the expression of MMP-1. In addition pattern-matched analysis of transcriptome and DMA methylome provide many new signature molecules regulated by CP and UVB. CP specifically modulated the expression of profilin-1 and involucrin by suppression of their DNA methylation. These results suggest that cacao extract may offer a protective effect against the photoaging process by epigenetic regulation of signature molecules, leading to an overall reduction in wrinkle formation.

 

 

Thomas Haffner

Vascular and cosmetic surgeon, Germany

Title: Blepharoplasty with orbicularis augmentation and orbicularis lifting

Time : 16:30 to 17:00

Speaker
Biography:

Thomas Haffner is a Board Certified Reconstructive, Vascular and Cosmetic Surgeon in Germany. He was trained in the Reconstructive-Plastic Surgery and Senology Section at the Semmelweis University, Budapest. He is specialized in Vascular Surgery and has worked as Department Leader in German clinics. He was a Resident Assistant under Professor Rettinger in Ulm. In 2000, he established his private clinic for vascular-reconstructive and aesthetic surgery in Cologne, Germany. His primary focus is the breast and facial surgery using minimal invasive and endoscopic methods. He invented the innovative vertical scar free reconstructive 3D mastopexy. 

Abstract:

Blepharoplasty is thought to be the simplest procedure of the upper eyelid. The resection of orbicularis muscle to a lesser or greater extent performed usually, without any goal and without consultation with the patient. By this way, the orbita will be seen much more opened, but also much more empty and hollow. All this cannot promote a youthful look, than youthful means also “full” that means filled and not hollow. The second great problem in every blepharoplasty is that the brows are pulled always downward after removing of a large amount of upper eyelid skin.

Method: The standard blepharoplasty is performed by saving and imbricating of the orbicular muscle with which an augmentation of the hollowed orbita is done. More than 200 cases were operated with this method. In further, five cases an additional orbicularis lifting blepharoplasty was made, by which the periorbicular, orbicular muscle dissected, elevated and anchored in a higher position.

Findings: The augmentation blepharoplasty rejuvenates the periorbita region bringing a youthful look in every case and no cases arise with skeletonized or older look. The scar quality was very good in 96% of the cases. Applying additional periorbicular myotomy, shifting and re-anchorage of the orbicularis muscle, a further improving of the brow-position and SOOF is achieved. The upper eyelid and brow region are "opened" with natural and discreet elevation of the brows and with restoration of the natural and youthful brow-tarsus distance.

Conclusions: The usual practice of simple blepharoplasty, which includes removing of the upper eyelid muscles without reason, should be reconsidered. Promoting of a skeletonized orbita by a young lady should be avoided and the orbicularis augmentation should be considered especially by older patients with thin skin envelope, before a blepharoplasty.